XIAFLEX^® Cost & Savings

Learn About Cost, Insurance Coverage, & The Zero Pay Program

Actual patient
compensated for his time.

The Zero Pay Program

With the Zero Pay Program, almost 9 out of 10 commercially insured patients should pay $0 out of pocket for XIAFLEX.^†

Eligible patients may save on their out-of-pocket costs for each vial of XIAFLEX. Some treatments may require two vials of XIAFLEX, and patients may save on both vials. Restrictions for patients apply. See restrictions, terms, and conditions.

If you have questions, we’re here to help. Call 1-877-XIAFLEX (1-877-942-3539) for more information.

How do I learn about my cost and coverage?

Get details about your cost and insurance coverage with this easy-to-use tool. Most get results within a few minutes.

Check your cost

How do I get XIAFLEX?

Your Hand Specialist may acquire XIAFLEX from either CVS Specialty Pharmacy or a Specialty Distributor.

When using CVS Specialty Pharmacy, both you and your Hand Specialist play roles in obtaining your prescription.

XIAFLEX is only available by prescription. Visit a Hand Specialist trained in XIAFLEX and ask about XIAFLEX for your Dupuytren's contracture.

In order to ship XIAFLEX to your Hand Specialist's office, CVS Specialty Pharmacy must first call and speak to you directly to confirm your personal information. If you miss them, call them back at 1-844-343-4221.

Watch the video to learn about getting XIAFLEX.

XIAFLEX Copay Brochure

Learn more about the XIAFLEX® Copay Assistance Program with this brochure. Eligible patients may save on their out-of-pocket costs for each vial of XIAFLEX. Terms and conditions apply.

Copay Reimbursement Form

Complete and submit this form to help with copay reimbursement.

Some helpful hints while your results load:

IMPORTANT SAFETY INFORMATION

Do not receive XIAFLEX^® if you have had an allergic reaction to collagenase clostridium histolyticum or any of the ingredients in XIAFLEX, or to any other collagenase product. See the end of the Medication Guide for a complete list of ingredients in XIAFLEX.

XIAFLEX can cause serious side effects, including:

Tendon rupture or ligament damage. Receiving an injection of XIAFLEX may cause damage to a tendon or ligament in your hand and cause it to break or weaken. This could require surgery to fix the damaged tendon or ligament. Call your healthcare provider right away if you have trouble bending your injected finger (towards the wrist) after the swelling goes down or you have problems using your treated hand after your follow-up visit
Nerve injury or other serious injury of the hand. After finger procedures, some people developed tears in the skin (lacerations), and local skin and soft-tissue necrosis (death of skin cells). Some lacerations and necrosis required skin grafting, or other surgery including amputation. Call your healthcare provider right away if you get numbness, tingling, increased pain, or tears in the skin (laceration) in your treated finger or hand after your injection or after your follow-up visit
Hypersensitivity reactions, including anaphylaxis. Severe allergic reactions can happen in people who receive XIAFLEX because it contains foreign proteins. Call your healthcare provider right away if you have any of these symptoms of an allergic reaction after an injection of XIAFLEX:
- hives
- swollen face
- breathing trouble
- chest pain
- low blood pressure
- dizziness or fainting
Fainting. Fainting (passing out) or near fainting can happen in people who receive XIAFLEX, especially following finger procedures
If you have dizziness or feel faint after receiving XIAFLEX, lie down until the symptoms go away.
Increased chance of bleeding. Bleeding or bruising at the injection site can happen in people who receive XIAFLEX. Talk to your healthcare provider if you have a problem with your blood clotting. XIAFLEX may not be right for you.

Before receiving XIAFLEX, tell your healthcare provider if you have had an allergic reaction to a previous XIAFLEX injection, or have a bleeding problem or any other medical conditions. Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Using XIAFLEX with certain other medicines can cause serious side effects. Especially tell your healthcare provider if you take medicines to thin your blood (anticoagulants). If you are told to stop taking a blood thinner before your XIAFLEX injection, your healthcare provider should tell you when to restart the blood thinner. Ask your healthcare provider or pharmacist for a list of these medicines if you are unsure.

The most common side effects with XIAFLEX for the treatment of Dupuytren’s contracture include:

swelling of the injection site or the hand
bruising or bleeding at the injection site
pain or tenderness of the injection site or the hand
swelling of the lymph nodes (glands) in the elbow or armpit
itching
breaks in the skin
redness or warmth of the skin
pain in the armpit

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects with XIAFLEX. For more information, ask your healthcare provider or pharmacist.

WHAT IS XIAFLEX^®?

XIAFLEX is a prescription medicine used to treat adults with Dupuytren’s contracture when a “cord” can be felt. It is not known if XIAFLEX is safe and effective in children under the age of 18.

Rx Only

Click for full Prescribing Information, including Medication Guide.

^†Most eligible patients with commercial insurance plans should pay a $0 copay for XIAFLEX^®. Predictions based on historical analysis of claims filed September 2022 through August 2023.

XIAFLEX® Cost & Savings