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Prescription treatment for adults with Dupuytren’s contracture when a “cord” can be felt

CARING FOR YOUR HAND AFTER TREATMENT

After your visit, your doctor will provide instructions on how to care for your hand. Some directions include:

  • Asking you to do simple finger exercises daily
  • Instructing you to wear a splint at bedtime to keep your finger(s) straight
  • Letting you know how long to wait before you can start your normal activities with the treated hand

Note: Dupuytren’s contracture may return no matter what treatment is used.

Examples of at-home finger exercises

After treatment with XIAFLEX®, your doctor may prescribe finger exercises for you to perform at home. Do the finger exercises each day as instructed by your doctor. Here are some examples of at-home finger exercises.

Exercise 1

Lay your hand flat on the table. Raise each finger up one at a time; hold for 5 seconds; repeat 10 times. Repeat the exercise 4 times a day.

Finger raising exercise at home after Dupuytren's contracture treatment.

Exercise 2

Lay your hand flat on the table. Move each finger from side to side (like a windshield wiper) one at a time; repeat 10 times. Repeat the exercise 4 times a day.

Side-to-side finger exercise at home

Exercise 3

Bend only the top 2 joints of all fingers keeping your knuckles straight. Arch your knuckles back 10 times in a row. Repeat the exercise 4 times a day.

Finger bending exercise at home

Exercise 4

Use the unaffected hand to gently straighten the affected finger 10 times, holding for 5 to 10 seconds. Repeat the exercise 4 times a day.

This information should not take the place of talking with your doctor or healthcare professional. If you have any questions, talk to your doctor or pharmacist.

The finger exercises are also available to print out.

Download the finger exercises

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Important Safety Information for XIAFLEX®

Do not receive XIAFLEX® if you have had an allergic reaction to collagenase clostridium histolyticum or any of the ingredients in XIAFLEX®, or to any other collagenase product. See the end of the Medication Guide for a complete list of ingredients in XIAFLEX®.

XIAFLEX® can cause serious side effects, including:

  • Tendon rupture or ligament damage. Receiving an injection of XIAFLEX® may cause damage to a tendon or ligament in your hand and cause it to break or weaken. This could require surgery to fix the damaged tendon or ligament. Call your healthcare provider right away if you have trouble bending your injected finger (towards the wrist) after the swelling goes down or you have problems using your treated hand after your follow-up visit
  • Nerve injury or other serious injury of the hand. Call your healthcare provider right away if you get numbness, tingling, increased pain, or tears in the skin (laceration) in your treated finger or hand after your injection or after your follow-up visit
  • Hypersensitivity reactions, including anaphylaxis. Severe allergic reactions can happen in people who receive XIAFLEX® because it contains foreign proteins. Call your healthcare provider right away if you have any of these symptoms of an allergic reaction after an injection of XIAFLEX®:
    • hives
    • swollen face
    • breathing trouble
    • chest pain
    • low blood pressure
    • dizziness or fainting
  • Increased chance of bleeding. Bleeding or bruising at the injection site can happen in people who receive XIAFLEX®. Talk to your healthcare provider if you have a problem with your blood clotting. XIAFLEX® may not be right for you.

Before receiving XIAFLEX®, tell your healthcare provider if you have had an allergic reaction to a previous XIAFLEX® injection, or have a bleeding problem or any other medical conditions. Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Using XIAFLEX® with certain other medicines can cause serious side effects. Especially tell your healthcare provider if you take medicines to thin your blood (anticoagulants). If you are told to stop taking a blood thinner before your XIAFLEX® injection, your healthcare provider should tell you when to restart the blood thinner. Ask your healthcare provider or pharmacist for a list of these medicines if you are unsure.

The most common side effects with XIAFLEX® for the treatment of Dupuytren’s contracture include:

  • swelling of the injection site or the hand
  • bruising or bleeding at the injection site
  • pain or tenderness of the injection site or the hand
  • swelling of the lymph nodes (glands) in the elbow or armpit
  • itching
  • breaks in the skin
  • redness or warmth of the skin
  • pain in the armpit

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects with XIAFLEX®. For more information, ask your healthcare provider or pharmacist.

What is XIAFLEX®?

XIAFLEX® is a prescription medicine used to treat adults with Dupuytren’s contracture when a “cord” can be felt. It is not known if XIAFLEX® is safe and effective in children under the age of 18.

Please see the full Prescribing Information, including Medication Guide.