Dupuytren’s contracture is a progressive disease of the hand that can affect patients for a lifetime1
There is no available cure, and a contracture can recur following all treatment options1

Characteristics of the condition
- A collagen-containing cord forms in the palm and finger2
- The cord thickens, shortens, and may pull the finger toward the palm2,3

Fibroproliferative disease
- Increased synthesis of types I and III collagen and reduced ability to break down excess collagen results in collagen deposits4-6
- Disease recurrence is highly variable and may be due to aggressiveness of disease and prior treatment modality1

Inherited and non-inherited risks1,4
- Caucasian males, northern European descent
- Diabetes, cigarette smoking, older age, menopause, and alcohol consumption are risk factors associated with the disease

Prevalence and treatment delays
- Estimated to affect >14 million people in the United States7
- 23.1 months mean time between symptom onset and seeing a physician8*
*Data based on Web-based survey that included 192 treatment-seeking patients who self-reported Dupuytren’s diagnosis and/or surgical/needle aponeurotomy treatment.8