XIAFLEX® helps disrupt the cord without requiring an incision and can be administered in the office1,2†
*In clinical trials, XIAFLEX® was used to treat 20°–100° MP contractures and 20°–80° PIP contractures.1
†Promptly evaluate signs and symptoms of serious injury to the injected finger/hand, as surgical intervention may be required.1
Inject the full clinical dose of 0.58 mg of XIAFLEX® into 3 locations of a palpable cord. Two affected joints in the same hand can be treated in one office visit.1Learn more
~24–72 hours after the injection, if a contracture remains, gently extend the finger to facilitate a cord disruption. Local anesthesia may be used. Skin splitting may occur.1Learn more
Following treatment, patients should be fit with a splint to be worn at bedtime for up to 4 months and perform finger exercises several times a day for several months.1Learn more
References: 1. XIAFLEX. Prescribing information. Endo Pharmaceuticals Inc. 2. Hurst LC, Badalamente MA, Hentz VR, et al. Injectable collagenase clostridium histolyticum for Dupuytren’s contracture. N Engl J Med. 2009;361(10):968-979.