Wondering if XIAFLEX® is right for you? XIAFLEX® is the first and only FDA-approved nonsurgical treatment for adults with Dupuytren's contracture when a "cord" can be felt.
ASK YOUR HCP ABOUT A NONSURGICAL TREATMENT OPTION
What is XIAFLEX®?
XIAFLEX® is a prescription medicine used to treat adults with Dupuytren’s contracture when a “cord” can be felt. XIAFLEX® is injected directly into the cord that is causing your finger to be bent.
XIAFLEX® is administered
- In your HCP's office
- By a hand specialist with training specifically for XIAFLEX®
- With no general anesthesia required
XIAFLEX® should be injected into a cord by a specialist who is experienced in injection procedures of the hand and treating people with Dupuytren’s contracture. XIAFLEX® can cause serious side effects such as tendon rupture or ligament damage.
Your HCP may consider treatment with XIAFLEX® if you have:
- Contractures ranging from less severe to more severe
- Multiple contractures in 1 hand. Up to 2 cords in 1 hand may be treated during 1 office visit.
- Contractures that have come back
How XIAFLEX® works
The enzymes in XIAFLEX® may break down the collagen in the cord. At a follow-up visit 1 to 3 days after the injection, if you still have the cord, your HCP may try to extend the finger to "break" the cord and try to straighten your finger. Your HCP may use local anesthetic during this procedure.
Demonstrated in clinical studies
Studies show that prescription XIAFLEX®, along with a finger extension procedure, may help straighten or nearly straighten the affected finger and improve range of motion after up to 3 injections.
In one clinical study, 64% of 203 patients (versus 7% of 103 patients receiving placebo) had a straight or nearly straight finger after up to 3 XIAFLEX® injections and finger extension procedures.
In a second clinical study, 44% of 45 patients (versus 5% of 21 patients receiving placebo) had a straight or nearly straight finger after up to 3 XIAFLEX® injections and finger extension procedures.
Since 2010, it is estimated that more than 100,000 patients have been treated with XIAFLEX®.*
*Through May 2017.